Why we're launching the Frontier Biodefense Fellowship
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People say, “Gee, I don’t want to be a machine.” They’re thinking of the machines they know today, and that’s not the kind of machine I’m talking about. I’m talking about a machine—and we’ll probably need a different word by then—that’s just as subtle and supple and emotional as humans are today, and even more so.
While this first construct—dubbed M. mycoides JCVI-syn1.0, is a proof of concept, the tools and technologies developed to create this cell hold great promise for application in so many critical areas. Throughout the course of this work, the team contemplated, discussed, and engaged in outside review of the ethical and societal implications of their work. The ability to routinely write the software of life will usher in a new era in science, and with it, new products and applications such as advanced biofuels, clean water technology, and new vaccines and medicines.*golfclap*
When thinking about existential risks it is important to have a sense of what the stakes are, and not just think "that is bad" - some things can be many orders of magnitude worse than others. At the same time, as Nick Bostrom pointed out, we have rather minimal research on how to prevent human extinction, about the same size as the literature on dung beetle reproduction. Toby Ord has pointed out that some charities can be up to 10,000 times more efficient in providing health than others (in terms of years of life per dollar donated), just because they focus on particular very effective means. Aubrey de Grey showed a pretty minor advance in biogerontology that was hailed in the media as "the secret of ageing", while rattling of a series of papers with far more profound implications that nobody outside the field has heard of. A graph of cost and size of carbon abatement methods clearly shows that some fix a vastly bigger chunk than others.
The philosophy that accepts death must itself be considered dead,
its questions meaningless,
its consolations worn out.
- Alan Harrington