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Betterhumans > Cause of Aging Confirmed

Genetic mutations that accumulate in the DNA of mitochondria—the power plants in cells—determine the lifespan of mice, confirming a cause of aging and suggesting ways to slow it down.

The findings, by researchers at the Karolinska Institute in Stockholm, Sweden, reveal a fundamental biological mechanism underlying the aging process.

Mice With Defective Mitochondrial DNA Repair Gene Age More Rapidly

University of Cambridge biogerontologist Aubrey de Grey argues that the presence of 13 of the mitochondrial genes actually in the mitochondria makes those genes something akin to an Achilles Heel for human aging.

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